In the world of global public health research, patients often have little to no voice in conversations around clinical research, even though the many health management tools, practices, and procedures resulting from this research affect patients the most. Dr. Soham Bandyopadhyay, academic clinician at the University of Oxford and a teaching associate for the Oxford University Global Surgery Group, seeks to change this.
Dr. Alma Faust spent the majority of her career pioneering strategies and tactics that helped researchers - and institutions - become more competitive with grant funding efforts. In this Q&A article, she explains how preprints can help advance a research enterprise, strengthen grant applications, and move science forward more quickly in the process.
This week, Research Square celebrates a new milestone: 100,000 preprints posted on our server. Here we briefly look back for the ten most influential preprints ever posted - within the science community and among the public at large.
Longtime biomedical research librarian Frank Norman and other leaders at the Francis Crick Institute (a.k.a. the Crick) are encouraging their researchers to post preprints of their work. We connected with Norman for an interview to learn why. We also gathered his insights on preprints and their role in the evolution of scholarly publishing.
Preprints are accelerating the speed and openness of research, but we have the opportunity to use new and innovative services, like Smart Citations, to help us evaluate and discover how other scientists have interpreted or tested these scholarly works. Josh Nicholson, co-founder and CEO of scite.ai explains in this guest post.
Being mindful of possible confounders sharpens your ability to recognize potentially biased relationships and to think critically about associations that seem valid at first glance.
Misinformation is on the rise, so what are some of the specific ways that information standards can help address misinformation? Guest author Alice Meadows, Director of Community Engagement at the National Information Standards Organization (NISO), highlights some of the knowledge and solutions brought forth during the 2021 NISO Plus 2021 meeting (held virtually last February), as well as some of the more recent efforts resulting from this meeting.
Statistics are a very important component of scientific research. While statistics play an important role in research, the details of the statistical methods used in a study are often incomplete. Underspecified methods are a lot like providing only part of a recipe. When details aren’t clearly specified, the quality of the end-product will be variable. In this article, we discuss how to describe your statistical methods and results to ensure that other scientists are provided with the information needed to accurately repeat your analysis.
Pritam Sukul, senior medical scientist at the University Medicine Rostock in Germany, learned about preprints and Research Square by chance, while simply searching for a paper. After researching the topic, he posted a preprint that gained significant attention in the medical science world. Research Square’s Phil Bogdan, met with Sukul to discuss his experiences and opinions on preprints, the current state of scholarly publishing, and how, in his opinion, preprints can integrate with journals.
Kater Hake has been conducting and managing plant science research for more than 40 years. Like many researchers outside the clinical and physical sciences, Hake began to recognize preprints’ potential for his own plant and agricultural sciences community, particularly for rapidly advancing research, protecting it from intellectual property theft, and making it available to agriculture’s broad, interconnected community of scientists and industry professionals.
Due to various factors such as waning immunity, vaccine hesitancy, and disparities in vaccine distribution, total herd immunity is rarely achieved.
Ultimately, the union of preprints with evidence-based medicine (EBM) has the potential to enhance the accuracy and comprehensiveness of clinical recommendations. Preprints lead the future of scientific publishing, and EBM is a domain that will benefit from this unbiased researcher-driven dissemination mechanism.
Journals generally require information about ethics committee approval and informed consent for all manuscripts that involve human subjects. Due to the broad definition of “human subjects research”, you may have questions about whether your study falls into this category and what information will be required by journals when you are ready to publish.
An in silico study is one performed via simulation on a computer. In silico simulations are frequently used to predict how a compound will react with proteins in the body or with pathogens.
Research Square has grown at a rapid pace in 2020 - and continues to do so in 2021. This infographic underscores our growth in “The Year of the Preprint.”
If you plan to publish a study involving animals, missing information about ethical approval and animal welfare can delay peer review and even result in rejection of your manuscript.
Dr. Naomi Moris, Professor Alfonso Martinez Arias, and colleagues developed a step-by-step protocol describing a process for successfully generating human gastruloids from human embryonic stem cells (ESCs) for use in a lab setting. They posted it as an independent research object on the Protocol Exchange, which is making reproducibility, transparency, and shareability easier.
In addition to helping others reproduce your results, adding sufficient methodological details also helps readers understand the conditions in which your results are applicable. This saves others from spending tons of time and effort on reproducing results and helps move science forward more quickly.
A preprint is a complete scientific manuscript uploaded by its authors to a public platform.
The next time you read “A study shows…," do not accept the statement and study at face value. To find the truth - or at least the most likely truth - it is necessary to challenge everything.
Join one research team on their first voyage through the world of preprinting, a trip that logged 20 citations, 5,500 pdf downloads, 168,083 HTML page views, and an Altmetric score of over 3,700—before their manuscript was published in Nature Immunology.
An animal model is a non-human species that is used in experiments that would not be feasible or ethical to conduct in humans.
In 2020, preprints became the scientific community’s most significant vehicle for research communication during the COVID-19 pandemic.
Research papers are becoming more than just static articles published in refereed journals. Protocols and other “research objects” are making reproducibility, transparency, and shareability much easier. Meet the Protocol Exchange, which fosters these and many other benefits for the researchers who use them.
[Science] has been plagued by a dissemination crisis, where research that could be published is blocked by publishers, and the quality and validity of research that is published is too often questionable or outright false.
Consider the sample size used in the study. A statistically significant p value does not necessarily imply importance.
[The] interpretation of clinical research is based around probabilities. If the trial’s methods are poor, there is a greater likelihood that the results do not estimate the true sample mean and/or that the results will not translate from the studied population to another population.
The use of masks, together with other precautionary measures, significantly reduces the spread of COVID-19 infection; however, the effects of masks on children have not been widely studied.
As awareness around preprints grows and the practice is increasingly adopted, encountering multiple versions of the same work will become a normal aspect of navigating the literature.
Toward the end of November 2020, Research Square celebrated its 50,000th preprint, capping off a spectacular rise for the platform and for preprints in general. Research Square also brought several industry firsts to scholarly publishing this year.
To understand if research can be trusted, a study must be critically appraised to assess if methodological weaknesses may have influenced the results, deviating their estimations away from the truth.
Research Square Company is pleased to announce the hire of Helen Tian as its General Manager of Researcher Solutions in Greater China.
Consider what type of cell line(s) the researchers used. Does the cell line act as a good model for the topic being studied? For example, do the researchers use breast cancer cell lines for a study on breast cancer, or are they using prostate cancer cells?
Following a successful beta in August, Research Square has directly integrated a new automated editing service that is capable of making high-quality technical manuscript edits in just 20 minutes.
Over 355 years have passed since the primordial oral preprint paradigm was established, where researchers could rapidly share their work with the community but could not claim rights in print to their content due to the impermanence of oration.
Research Square, a multidisciplinary publishing platform for preprints, has surpassed 50,000 submissions since its debut in October 2018.
Here, we present an example preprint that underwent our evaluation and earned a Methods Badge on the Research Square platform.
Biased information -- in research and in everyday life -- attempts to change your mind and how you think. It is therefore an important skill to be aware of bias and know how to identify, analyze, and assess biased information properly.
Identifying the specific reagents, materials, and tools used to perform research is critical to its reproducibility.
In celebration of Open Access Week 2020 and its theme, “Open with Purpose: Taking Action to Build Structural Equity and Inclusion,” we’ve collected and summarized some of the most significant stories of this eventful year.
Learn how Open Access publication is growing, how governmental mandates have been propelling the movement forward, and how this affects authors when publishing.
How publishers and authors can benefit from Artificial Intelligence-based services designed to make manuscript preparation seamless
How to watch out for predatory journals in the Open Access world
Clinical trials of treatments and vaccines for COVID-19 have been in the news constantly this year. Differences in design, size, and analysis can make it difficult to compare these studies and apply their findings to an individual’s medical care.
Research Square has launched a beta trial of its new automated Open Science Assessment tool, which can help authors enhance the quality of their research and the robustness of their scientific reporting.
With the persistent pressure to publish often, it can be difficult to keep statistical reporting top of mind, but the details of data analysis are essential.
“As an integrated part of the preprinting process on our platform, SciScore will help authors ensure the science behind their manuscripts is better prepared for peer review.”
Research Square Editor in Chief, Michele Avissar-Whiting, delivered a short talk on the topic of preprints and peer review.
To remediate peer review and optimize how science is disseminated and evaluated, the dynamics of the publication process as a whole must be reimagined.
A tour of how peer review builds trust across the various steps of publication
The authors of this study analyzed records from a long-term elder care facility that was converted into a COVID-19 healthcare facility from March 15 to June 5, 2020.
Research Square received the 2020 Best Places to Work award by the Triangle Business Journal this week. It was one of 50 companies to receive this honor in the Large Company category.
Christensen has solidified his place as a thought leader in scholarly publishing during his 20-year career, holding a range of global leadership roles in business development, sales, and editorial management.
The adage “Publish or Perish” suddenly took on a starkly literal character. The name of the game now was speed and maximum visibility, and preprinting offers both at no cost to authors.
New service uses artificial intelligence to edit papers.
Reporting in scientific studies is broken - and it needs to be fixed.
As with any peer-reviewed paper, a preprint should be read in full and limitations carefully noted for inclusion in the piece.
Michele Avissar-Whiting, PhD, to lead the editorial vision for Research Square.
Announcing the expansion of our In Review service to Nature Research journals
Badges are virtual "stamps" signifying that a paper has passed certain quality checks, and they can benefit authors, readers, and science as a whole.
Research Square is now offering badges in Methods or Statistics Reporting to researchers who post a preprint to its multidisciplinary preprint platform, also known as Research Square.
Research Square, the company behind the world’s fastest-growing preprint platform, is partnering with Dimensions to provide early citation data on preprints.
Research Square, the company behind the world’s fastest-growing preprint platform, is launching a blog as an educational resource for researchers.
Research Square, known for their multidisciplinary preprint platform, reached 20,000 preprints just 18 months after its launch in 2018.
Preprints represent a unique publication type that can provide distinct advantages when used to supplement traditional peer-reviewed publications.
Preprinting can increase the impact and decrease the time to publication of preprinted manuscripts that are eventually submitted to journals.
The event was set to be held in Washington, DC, but in light of current circumstances surrounding COVID-19, it has been transitioned to a remote meeting.
AJE and Research Square jointly hosted an online event as part of Peer Review Week, an annual event in scholarly publishing.
Rachel Burley has spent more than eighteen years in senior roles in the publishing industry and joins Research Square from Springer Nature.
Learn more about Plan S and how this funding mandate will impact researchers.
Researchers who post a preprint to Research Square can now access AJE author services and Research Square videos to improve their manuscript and better communicate their findings.
Researchers can now post their manuscript directly to the platform as a preprint and gain early feedback from the scientific community.
The coalition was formed to discuss and address issues of diversity and inclusion within the Scholarly Publishing industry
Peer Review Week 2018’s theme focused on Diversity and Inclusion within academia, peer review, and research publication.
Here are a few suggestions for using Twitter to find new readers (and potential citations).
Videos are a great tool to help promote your research. Watch our video to find out how to share them to increase the impact of your work.
The meetings are intended to foster conversations and the sharing of knowledge among the scholarly publishing community.
Preprints are research papers shared before peer review. Here we discuss the benefits to authors including rapid credit, visibility & feedback.
Hashtags make it easier for others to find your research online. Make sure you choose words that are relevant to your work so that you maximize engagement.
Learn how to see how people are engaging with your research papers and research videos online.
Make use of online sites and networks like LinkedIn and ResearchGate to improve your online visibility and highlight the information about your research that you want others to see.