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Method Article
Animal model of allergy and asthma; protocol for researches
Seyyed Shamsadin Athari
Department of Immunology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran
Corresponding Author
ORCiD: https://orcid.org/0000-0002-6355-6378
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Allergic diseases and asthma are an important problem in health system and effects large amounts of people in the worlds. Exposure to outdoor and indoor allergens promote the sensitization towards these allergens. Th2 cytokines are main stimulators allergic diseases initiation. Allergic diseases similar to other diseases have been studied in animal for understanding of pathophysiology and treatments. Animal models provide a potential approach to investigation of the pathophysiology, mechanism and drugs designing for allergy and asthma. Physicians and veterinarians with collaboration in this field could improve best animal model. In this review, it will be discussed the various models (especially in mouse) and protocols by focusing on the allergic diseases. Animal models in allergy field, are applicable for important goals. Moral discussion in all procedures should be remarkable.
Keywords
Allergic diseases, Asthma, Immune system, Model, Animal
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This is a preprint. It has not completed peer review.
Method Article
Animal model of allergy and asthma; protocol for researches
Seyyed Shamsadin Athari
Department of Immunology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran
Corresponding Author
ORCiD: https://orcid.org/0000-0002-6355-6378
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
Version 1
Posted 11 Sep, 2019
No community comments so far
Metrics
Comments: 0
HTML Views: ...
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Allergic diseases and asthma are an important problem in health system and effects large amounts of people in the worlds. Exposure to outdoor and indoor allergens promote the sensitization towards these allergens. Th2 cytokines are main stimulators allergic diseases initiation. Allergic diseases similar to other diseases have been studied in animal for understanding of pathophysiology and treatments. Animal models provide a potential approach to investigation of the pathophysiology, mechanism and drugs designing for allergy and asthma. Physicians and veterinarians with collaboration in this field could improve best animal model. In this review, it will be discussed the various models (especially in mouse) and protocols by focusing on the allergic diseases. Animal models in allergy field, are applicable for important goals. Moral discussion in all procedures should be remarkable.
Figure 1
Figure 2
Figure 3
Figure 4
Figure 5
Figure 6
Figure 7
Figure 8