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Method Article
Daniel J Corsi
Ottawa Hospital Research Institute/Institut de recherche de l'hopital d'Ottawa
Corresponding Author
ORCiD: https://orcid.org/0000-0001-7063-3354
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Cannabis use in pregnancy has increased, and many women continue to use it throughout pregnancy. With the legalization of recreational cannabis in many jurisdictions, there is concern about potentially adverse childhood outcomes related to prenatal exposure.4 Using the provincial birth registry containing information on cannabis use during pregnancy, we will assemble a large, population-based cohort of children born to mothers in Ontario, with and without prenatal exposure to cannabis from birth to 10 years of age. A series of investigations will examine the health effects of prenatal cannabis exposure on child outcomes using novel methods to address confounding. We will link pregnancy and birth data to provincial health administrative databases to ascertain child neurodevelopmental outcomes. The unique aspect of our proposed research is that we plan to utilize an existing population-based perinatal registry combined with administrative datasets for long-term follow up of children using a rich set of covariates and potential confounders to assess the association with cannabis exposure on pregnancy and perinatal outcomes and into childhood.
Keywords
epidemiology, autism spectrum disorder, neurodevelopment, cannabis, pregnancy, cohort studies, birth registry, Canada
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Associated Publications
An open repository of community-contributed protocols sponsored by Nature Research.
Learn more about Protocol Exchange
Method Article
Daniel J Corsi
Ottawa Hospital Research Institute/Institut de recherche de l'hopital d'Ottawa
Corresponding Author
ORCiD: https://orcid.org/0000-0001-7063-3354
Version History
CURRENT STATUS: Posted
Version 1
Posted 10 Aug, 2020
No community comments so far
Metrics
Comments: 0
HTML Views: ...
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Cannabis use in pregnancy has increased, and many women continue to use it throughout pregnancy. With the legalization of recreational cannabis in many jurisdictions, there is concern about potentially adverse childhood outcomes related to prenatal exposure.4 Using the provincial birth registry containing information on cannabis use during pregnancy, we will assemble a large, population-based cohort of children born to mothers in Ontario, with and without prenatal exposure to cannabis from birth to 10 years of age. A series of investigations will examine the health effects of prenatal cannabis exposure on child outcomes using novel methods to address confounding. We will link pregnancy and birth data to provincial health administrative databases to ascertain child neurodevelopmental outcomes. The unique aspect of our proposed research is that we plan to utilize an existing population-based perinatal registry combined with administrative datasets for long-term follow up of children using a rich set of covariates and potential confounders to assess the association with cannabis exposure on pregnancy and perinatal outcomes and into childhood.
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