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Method Article
Protocol for the pig liver ischemia/reperfusion injury
Eric Felli
Institute of Physiology, EA3072 Mitochondria Respiration and Oxidative Stress, University of Strasbourg, Strasbourg, France
Corresponding Author
ORCiD: https://orcid.org/0000-0002-5664-6746
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This work is licensed under a CC BY 4.0 License. Read Full License
Liver ischemia/reperfusion injury (IRI) is a dreadful vascular complication, which leads to liver damage. It is often associated with graft loss in liver transplantation and with a higher morbidity and mortality. IRI can have different causes, such as inflow clumping during surgical procedures in hepatic resection, liver transplantation, trauma, as well as during the stenosis of the vasculature caused by cancer. Here, we show a detailed IRI protocol in a porcine model.
Keywords
ischemia reperfusion injury, IRI, Liver, hepatic ischemia, liver ischemia, pig hepatic ischemia
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Gastroenterology
Associated Publications
Hyperspectral evaluation of hepatic oxygenation in a model of total vs. arterial liver ischaemia
by Eric Felli, Mahdi Al-Taher, Toby Collins, +11
Scientific Reports (22 September, 2020)
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This is a preprint. It has not completed peer review.
Method Article
Protocol for the pig liver ischemia/reperfusion injury
Eric Felli
Institute of Physiology, EA3072 Mitochondria Respiration and Oxidative Stress, University of Strasbourg, Strasbourg, France
Corresponding Author
ORCiD: https://orcid.org/0000-0002-5664-6746
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
Version 1
Posted 30 Nov, 2020
No community comments so far
Metrics
Comments: 0
HTML Views: ...
Subject Areas
Gastroenterology
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Liver ischemia/reperfusion injury (IRI) is a dreadful vascular complication, which leads to liver damage. It is often associated with graft loss in liver transplantation and with a higher morbidity and mortality. IRI can have different causes, such as inflow clumping during surgical procedures in hepatic resection, liver transplantation, trauma, as well as during the stenosis of the vasculature caused by cancer. Here, we show a detailed IRI protocol in a porcine model.
Figure 1
Associated Publications
Hyperspectral evaluation of hepatic oxygenation in a model of total vs. arterial liver ischaemia
by Eric Felli, Mahdi Al-Taher, Toby Collins, +11
Scientific Reports (22 September, 2020)