Mass Spectrometry Imaging of Invisible Micro-Patterns on Graphene Substrate
Invisible micro-patterns of trace amount molecules can be recognized through the mass spectrometry (MS) imaging technique on the engineered graphene film without additional chemicals such as organic matrix. The micro-patterns can be prepared in a controlled manner, where simple stamping was employed and diluted solution of molecules was used as the invisible ink. It is noted that due to the low concentration (pmol/µL) and detection of limit (fmol) for detection and imaging achieved in this protocol, the engineered graphene paper can be applied in not only tissue blotting for small metabolites and lipids molecules, but also forensic study to track trace amount of chemicals (such as drugs) in the latent fingerprint and record/monitor the invisible micro-pattern of specific molecules.
Figure 1
I am interested in this writing on Graphene Substrate. Can I get this full article as a PDF? Thanks
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I am interested in this writing on Graphene Substrate. Can I get this full article as a PDF? Thanks
Dear Sciker,Thank you for your comment on the Protocol Exchange article. We do not explicitly create PDFs of Protocol Exchange pieces, however if you wish for the article in that form you can use the 'Print' function on the article and adjust the settings to save the file as a PDF rather than outputting to a physical printer.Christopher Surridge Chief Editor, Nature Protocols
Posted 12 Mar, 2013
Mass Spectrometry Imaging of Invisible Micro-Patterns on Graphene Substrate
Posted 12 Mar, 2013
Invisible micro-patterns of trace amount molecules can be recognized through the mass spectrometry (MS) imaging technique on the engineered graphene film without additional chemicals such as organic matrix. The micro-patterns can be prepared in a controlled manner, where simple stamping was employed and diluted solution of molecules was used as the invisible ink. It is noted that due to the low concentration (pmol/µL) and detection of limit (fmol) for detection and imaging achieved in this protocol, the engineered graphene paper can be applied in not only tissue blotting for small metabolites and lipids molecules, but also forensic study to track trace amount of chemicals (such as drugs) in the latent fingerprint and record/monitor the invisible micro-pattern of specific molecules.
Figure 1
I am interested in this writing on Graphene Substrate. Can I get this full article as a PDF? Thanks
Dear Sciker,Thank you for your comment on the Protocol Exchange article. We do not explicitly create PDFs of Protocol Exchange pieces, however if you wish for the article in that form you can use the 'Print' function on the article and adjust the settings to save the file as a PDF rather than outputting to a physical printer.Christopher Surridge Chief Editor, Nature Protocols
I am interested in this writing on Graphene Substrate. Can I get this full article as a PDF? Thanks
Dear Sciker,Thank you for your comment on the Protocol Exchange article. We do not explicitly create PDFs of Protocol Exchange pieces, however if you wish for the article in that form you can use the 'Print' function on the article and adjust the settings to save the file as a PDF rather than outputting to a physical printer.Christopher Surridge Chief Editor, Nature Protocols
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