Polymer Coating of Quantum Dots for Excellent Colloidal Stability
In this protocol, a facile procedure for the transfer of quantum dots or different nanoparticles from organic synthesis into aqueous solution is described. Therefore, in the first step, poly(isobutylene maleic anhydride) is modified with hydrophobic side chains via amide bond formation. In the second step, this polymer is mixed with the nanoparticles and wrapped around them. The idea is let the side chains of the polymer intercalate with the inorganic ligands of the nanoparticles, and that the backbone of the polymer which is multifold charges due to the carboxylic groups leads to excellent water solubility. The nanoparticles are finally soluble in buffer solution and cleaned by gel electrophoresis or size exclusion chromatography. Additional functionalization of these nanoobjects is possible via amide bond formation.
Posted 28 Aug, 2012
Polymer Coating of Quantum Dots for Excellent Colloidal Stability
Posted 28 Aug, 2012
In this protocol, a facile procedure for the transfer of quantum dots or different nanoparticles from organic synthesis into aqueous solution is described. Therefore, in the first step, poly(isobutylene maleic anhydride) is modified with hydrophobic side chains via amide bond formation. In the second step, this polymer is mixed with the nanoparticles and wrapped around them. The idea is let the side chains of the polymer intercalate with the inorganic ligands of the nanoparticles, and that the backbone of the polymer which is multifold charges due to the carboxylic groups leads to excellent water solubility. The nanoparticles are finally soluble in buffer solution and cleaned by gel electrophoresis or size exclusion chromatography. Additional functionalization of these nanoobjects is possible via amide bond formation.
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