Successful cryopreservation of human ovarian cortex tissues using supercooling
THE EDITORS ARE RETRACTING THIS _PROTOCOL EXCHANGE_ PROTOCOL BECAUSE THE PAPER UPON WHICH IT IS BASED HAS BEEN RETRACTED.
The development of new method to cryopreserve human ovarian cortex tissues without damage is needed for the improvement of quality of life(QOL) of female cancer patients. Here we show novel cryopreservation method of human ovarian cortex tissues by using supercooling (S.C.) procedure. In our study, we have found that the stable expressions of 9 genes within human oocytes by using our S.C. procedure are necessary in order to produce human mature eggs and experience pregnancy with high safety profiles by In vitro fertilisation (IVF). Our method will be helpful in order to preserve fertility of female cancer patients.
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Editorial Note: Protocol Exchange has become aware of irregularities related to authors affiliations and the statement describing IRB approval in this protocol. The situation is being investigated.
Editorial Note: Sigeo Ihara, Yoshihiro Ohta and Yue Zhang have been removed from the author list at their request.The author list has changed from: Hisashi Moriguchi, Yue Zhang, Sigeo Ihara, Yoshihiro Ohta & Chifumi Satoto: Hisashi Moriguchi & Chifumi Sato
Editorial Note: Chifumi Sato has been removed from the author list at his request.The author list has changed from: Hisashi Moriguchi & Chifumi Satoto: Hisashi Moriguchi
Editorial Note: The above protocol was part of a research paper entitled "Successful cryopreservation of human ovarian cortex tissues using supercooling" which was published in Scientific Reports on 27 July 2012. The research paper has now been retracted - for further information on the retraction please go to http://www.nature.com/srep/2012/121108/srep00840/full/srep00840.html.
Editorial Note: Protocol Exchange has become aware of irregularities related to authors affiliations and the statement describing IRB approval in this protocol. The situation is being investigated.
Editorial Note: Sigeo Ihara, Yoshihiro Ohta and Yue Zhang have been removed from the author list at their request.The author list has changed from: Hisashi Moriguchi, Yue Zhang, Sigeo Ihara, Yoshihiro Ohta & Chifumi Satoto: Hisashi Moriguchi & Chifumi Sato
Editorial Note: Chifumi Sato has been removed from the author list at his request.The author list has changed from: Hisashi Moriguchi & Chifumi Satoto: Hisashi Moriguchi
Editorial Note: The above protocol was part of a research paper entitled "Successful cryopreservation of human ovarian cortex tissues using supercooling" which was published in Scientific Reports on 27 July 2012. The research paper has now been retracted - for further information on the retraction please go to http://www.nature.com/srep/2012/121108/srep00840/full/srep00840.html.
Posted 27 Jul, 2012
Successful cryopreservation of human ovarian cortex tissues using supercooling
Posted 27 Jul, 2012
THE EDITORS ARE RETRACTING THIS _PROTOCOL EXCHANGE_ PROTOCOL BECAUSE THE PAPER UPON WHICH IT IS BASED HAS BEEN RETRACTED.
The development of new method to cryopreserve human ovarian cortex tissues without damage is needed for the improvement of quality of life(QOL) of female cancer patients. Here we show novel cryopreservation method of human ovarian cortex tissues by using supercooling (S.C.) procedure. In our study, we have found that the stable expressions of 9 genes within human oocytes by using our S.C. procedure are necessary in order to produce human mature eggs and experience pregnancy with high safety profiles by In vitro fertilisation (IVF). Our method will be helpful in order to preserve fertility of female cancer patients.
Figure 1
Figure 2
Figure 3
Figure 4
Figure 5
Editorial Note: Protocol Exchange has become aware of irregularities related to authors affiliations and the statement describing IRB approval in this protocol. The situation is being investigated.
Editorial Note: Sigeo Ihara, Yoshihiro Ohta and Yue Zhang have been removed from the author list at their request.The author list has changed from: Hisashi Moriguchi, Yue Zhang, Sigeo Ihara, Yoshihiro Ohta & Chifumi Satoto: Hisashi Moriguchi & Chifumi Sato
Editorial Note: Chifumi Sato has been removed from the author list at his request.The author list has changed from: Hisashi Moriguchi & Chifumi Satoto: Hisashi Moriguchi
Editorial Note: The above protocol was part of a research paper entitled "Successful cryopreservation of human ovarian cortex tissues using supercooling" which was published in Scientific Reports on 27 July 2012. The research paper has now been retracted - for further information on the retraction please go to http://www.nature.com/srep/2012/121108/srep00840/full/srep00840.html.
Editorial Note: Protocol Exchange has become aware of irregularities related to authors affiliations and the statement describing IRB approval in this protocol. The situation is being investigated.
Editorial Note: Sigeo Ihara, Yoshihiro Ohta and Yue Zhang have been removed from the author list at their request.The author list has changed from: Hisashi Moriguchi, Yue Zhang, Sigeo Ihara, Yoshihiro Ohta & Chifumi Satoto: Hisashi Moriguchi & Chifumi Sato
Editorial Note: Chifumi Sato has been removed from the author list at his request.The author list has changed from: Hisashi Moriguchi & Chifumi Satoto: Hisashi Moriguchi
Editorial Note: The above protocol was part of a research paper entitled "Successful cryopreservation of human ovarian cortex tissues using supercooling" which was published in Scientific Reports on 27 July 2012. The research paper has now been retracted - for further information on the retraction please go to http://www.nature.com/srep/2012/121108/srep00840/full/srep00840.html.
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